tumoral cells (DSMZ)

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DSMZ tumoral cells
Tumoral Cells, supplied by DSMZ, used in various techniques. Bioz Stars score: 95/100, based on 162 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mkn+45/MKN-45/us12570761-762-18-15
Average 95 stars, based on 162 article reviews

tumoral cells - by Bioz Stars, 2026-10

95/100 stars

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Cell Culture:

Article Title: Anticancer effect of umbelliferone on MKN-45 and MIA PaCa-2 cell lines.
Article Snippet: In this study, the anticancer activity of umbelliferone (7-hydroxycoumarin-UMB) was investigated in MKN-45 human gastric cancer and MIA PaCa-2 human pancreatic cancer cells.. The cytotoxic effect of UMB on MKN45 and MIA PaCa-2 cells was determined by WST-8 cell viability assay; the effect on colony formation and migration potential by colony forming assay and wound healing/cell migration assay.. Apoptotic effect of UMB was determined by measuring the change in mitochondrial membrane potentials, reactive oxygen species levels, and Caspase-3 activities in cells.

Article Title: In Vitro Evaluation of the Safety and Efficacy of Cibisatamab Using Adult Stem Cell-Derived Organoids and Colorectal Cancer Spheroids.
Article Snippet: .. MKN-45 (ACC 409, DSMZ) and DLD-1 (ACC 278, DSMZ) were cultured in the medium recommended by the supplier in a humidified atmosphere of 5% CO2 at 37 ◦C. ..

Article Title: In Vitro Evaluation of the Safety and Efficacy of Cibisatamab Using Adult Stem Cell-Derived Organoids and Colorectal Cancer Spheroids
Article Snippet: .. MKN-45 (ACC 409, DSMZ) and DLD-1 (ACC 278, DSMZ) were cultured in the medium recommended by the supplier in a humidified atmosphere of 5% CO 2 at 37 °C. ..

Incubation:

Expressing:

Article Title: Polypeptides comprising immunoglobulin single variable domains targeting glypican-3 and T cell receptor
Article Snippet: .. The low or very low GPC3 expressing cell lines, which did not show any staining in ICC, were MKN-45 (DSMZ, clone ACC409; 1.5E4 receptors/cell), NCI-H23 (ATCC, clone CRL-5800; 2.6E3 receptors/cell), BxPC-3 (ATCC, clone CRL-1687; 1.5E3 receptors/cell) and NCI-H292 (ATCC, clone CRL-1848; 6E2 receptors/cell). ..

Article Title: Bispecific antibody molecules binding to CD3 and EGFRvIII
Article Snippet: .. MKN-45 (DSMZ ACC 409) is a human gastric adenocarcinoma cells expressing high levels of EGFRwt. ..

Article Title: Drug conjugates of cMET monoclonal binding agents, and uses thereof
Article Snippet: .. The cell lines tested were SNU-1 (ATCC, no expression of cMET, FIG. 18A), SNU-16 (ATCC, medium expression of cMET, FIG. 18B), SNU-620 (KCLB, high expression of cMET, FIG. 18C), MKN-45 (DSMZ, high expression of cMET, FIG. 18D), H441 (ATCC, medium expression of cMET, FIG. 19A), H1373 (ATCC, medium expression of cMET, FIG. 19B), H1975 (ATCC, medium expression of cMET, FIG. 19C), SNU-5 (ATCC, high expression of cMET, FIG. 19D), and H1573 (ATCC, medium expression of cMET, FIG. 19E). hD12-II and hD12-VII showed slightly higher potency in some medium and high cMET-expressing cell lines. ..

Staining:

Immunocytochemistry:

Transduction:

Article Title: Bispecific antigen binding molecules targeting OX40 and FAP
Article Snippet: .. MKN-45 (DSMZ; ACC409) were transduced with the Essen CellPlayer NucLight Red Lentivirus Reagent (Essenbioscience, Cat. No. 4476; EF1α, puromycin) at an MOI of 5 (TU/cell) in the presence of 8 μg/mL polybrene following the manufacturer's instructions to stable express a nuclear-restricted NucLight Red fluorescent protein. ..

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